Case 7 : Question : A 3 month old boy having hepatosplenomegaly. What is the diagnosis?
Case 6 : Question : A 5 year old girl with fever, cough, and dyspnea. What is the diagnosis?
Case 5 : Question : A 1 year old boy with choking, cough and wheezing. What is the diagnosis?
Case 4 : Question : Chest radiograph of a 3 month boy. What is the diagnosis?
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Question : A 3 month old boy having hepatosplenomegaly. What is the diagnosis?
Panruethai Trinavarat,M.D.
Assistant Professor.
Department of radiology, Faculty of medicine,
Chulalongkorn University
Case 7 :
Question :
A 3 month old boy having hepatosplenomegaly. What is the diagnosis?
Answer :
Langerhans cell histiocytosis
Chest involvement in LCH could be lung parenchymal lesion, enlarged mediastinal lymph nodes, and osteolytic lesion of the bony thorax.
For the pulmonary lesion, two forms have been described, depending on early or late stage. In early stage, the lung shows small nodules (1-5 mm diameter) some of which may cavitate. The fibrosis and cyst formation (each cyst is usually less than 1 cm size) are noted in later stage. Both forms are much better seen with CT scan. The chest radiograph findings consist of reticular, nodular, reticulonodular patterns, and honeycombing.
